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Arkh Patol ; 51(10): 18-25, 1989.
Artigo em Russo | MEDLINE | ID: mdl-2610600

RESUMO

Biopsy material from two groups of patients with liver diseases is studied. 12 patients with a high titer of total anti-delta (D)-antibodies are included into the 1st group. In this group, among patients with total antibodies to D-infection D-antigen in the liver tissue is found in 6 cases with a pronounced chronic aggressive hepatitis (CAH) and active liver cirrhosis (ALC). The 2nd group consisted of 30 patients with CAH and ALC and D-antigen was observed in 10 cases. Hepatocyte degeneration and pronounced lobular infiltration were the only distinctive feature of liver morphology in D-positive cases as compared to the D-negative ones. The presence of D-antigen always correlated with an active inflammatory process.


Assuntos
Hepatite D/patologia , Fígado/patologia , Adolescente , Adulto , Idoso , Antígenos Virais/análise , Biópsia , Doença Crônica , Feminino , Anticorpos Anti-Hepatite/análise , Hepatite D/enzimologia , Hepatite D/imunologia , Vírus Delta da Hepatite/imunologia , Histocitoquímica , Humanos , Fígado/enzimologia , Fígado/imunologia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
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